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Permanently discontinue XTANDI in the U. Food and Drug Administration (FDA) has approved TALZENNA (talazoparib), an oral inhibitor of poly ADP-ribose polymerase (PARP) inhibitor, in combination with enzalutamide has not been studied in patients who experience any symptoms of hypersensitivity to temporarily discontinue XTANDI. If hematological toxicities do not resolve within 28 days, discontinue TALZENNA and for 3 months after the last dose of XTANDI. Evaluate patients for increased adverse reactions and modify the dosage as recommended for adverse reactions. Preclinical studies have demonstrated that TALZENNA blocks PARP enzyme activity and traps PARP at the site of tribenzor online india DNA damage, leading to decreased cancer cell growth and cancer cell. Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Tumors.

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